Microenvironmental stiffness enhances glioma cell proliferation by stimulating epidermal growth factor receptor signaling.

The aggressive and rapidly lethal brain tumor glioblastoma (GBM) is associated with Welding Skid profound tissue stiffening and genomic lesions in key members of the epidermal growth factor receptor (EGFR) pathway.Previous studies from our laboratory have shown that increasing microenvironmental stiffness in culture can strongly enhance glioma cell

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Unveiling spindle cell lipoma: a radiological case report

Abstract Background Spindle cell lipoma is a benign adipocytic tumour, commonly occuring in the subcutis of posterior neck, upper back and shoulder, particularly in middle aged males.It is often composed of relatively equal ratio of fat and spindle cells, yet either component may predominate.Because of its variable ratio, a spindle cell lipoma may

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Revisiting the estimation of dinosaur growth rates.

Previous growth-rate studies covering 14 dinosaur taxa, as represented by 31 data sets, are critically examined and reanalyzed by using improved statistical techniques.The examination reveals that some previously reported results cannot be replicated by using the methods originally reported; results from new methods are in many cases different, in

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